6F7B: Crystal structure of the human Bub1 kinase domain in complex with BAY 1816032

PDB ID: 6F7BDownload
MMDB ID: 169820
PDB Deposition Date: 2017/12/8
Updated in MMDB: 2018/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 6F7B: monomeric; determined by author and by software (PISA)
Molecular Components in 6F7B
Label Count Molecule
Protein (1 molecule)
1
Mitotic Checkpoint Serine/threonine-protein Kinase Bub1
(Gene symbol: BUB1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
2-[3,5-bis(fluoranyl)-4-[[3-[5-methoxy-4-[(3-methoxypyridin-4-yl)amino]pyrimidin-2-yl]indazol-1-yl]methyl]phenoxy]ethanol2-[3,5-bis(fluoranyl)-4-[[3-[5-methoxy-4-[(3-methoxypyridin-4-yl)amino]pyrimidin-2-yl]indazol-1-yl]methyl]phenoxy]ethanol
2
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303