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6EGE:
Crystal structure of the unphosphorylated IRAK4 kinase domain Bound to a type I inhibitor
PDB ID:
6EGE
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MMDB ID:
172230
PDB Deposition Date:
2018/8/19
Updated in MMDB:
2019/12
Experimental Method:
x-ray diffraction
Resolution:
1.401 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 6EGE: dimeric; determined by author
Molecular Components in 6EGE
Label
Count
Molecule
Proteins (2 molecules)
D
A
2
Interleukin-1 Receptor-associated Kinase 4
(Gene symbol:
IRAK4
)
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303