6EGE: Crystal structure of the unphosphorylated IRAK4 kinase domain Bound to a type I inhibitor

PDB ID: 6EGEDownload
MMDB ID: 172230
PDB Deposition Date: 2018/8/19
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.401  Å
Source Organism:
Similar Structures:
Biological Unit for 6EGE: dimeric; determined by author
Molecular Components in 6EGE
Label Count Molecule
Proteins (2 molecules)
2
Interleukin-1 Receptor-associated Kinase 4
(Gene symbol: IRAK4)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamideN-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303