6DZ0: Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-4-((pent-4-yn-1-ylthio)methyl)pyrrolidin-3-ol

PDB ID: 6DZ0Download
MMDB ID: 173353
PDB Deposition Date: 2018/7/2
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.62  Å
Source Organism:
Similar Structures:
Biological Unit for 6DZ0: trimeric; determined by author and by software (PISA)
Molecular Components in 6DZ0
Label Count Molecule
Proteins (3 molecules)
3
S-methyl-5'-thioadenosine Phosphorylase
(Gene symbol: MTAP)
Molecule annotation
Chemicals and Non-standard biopolymers (22 molecules)
1
3
PHOSPHATE IONPHOSPHATE ION
2
15
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
3
(3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(pent-4-yn-1-yl)sulfanyl]methyl}pyrrolidin-3-ol(3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(pent-4-yn-1-yl)sulfanyl]methyl}pyrrolidin-3-ol
4
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303