6CUO: Ras:SOS:Ras in complex with a small molecule activator

PDB ID: 6CUODownload
MMDB ID: 172001
PDB Deposition Date: 2018/3/26
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.73  Å
Source Organism:
Similar Structures:
Biological Unit for 6CUO: trimeric; determined by author and by software (PISA)
Molecular Components in 6CUO
Label Count Molecule
Proteins (3 molecules)
1
Gtpase Hras
(Gene symbol: HRAS)
Molecule annotation
1
SON of Sevenless Homolog 1
(Gene symbol: SOS1)
Molecule annotation
1
Gtpase Hras
(Gene symbol: HRAS)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
2
1
MAGNESIUM IONMAGNESIUM ION
3
6
FORMIC ACIDFORMIC ACID
4
1
N~2~-(3-chlorophenyl)-N~4~-[(furan-2-yl)methyl]quinazoline-2,4-diamineN~2~-(3-chlorophenyl)-N~4~-[(furan-2-yl)methyl]quinazoline-2,4-diamine
5
2
GLYCEROLGLYCEROL
6
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303