6C2T: Aurora A ligand complex

PDB ID: 6C2TDownload
MMDB ID: 170628
PDB Deposition Date: 2018/1/8
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 1.73  Å
Source Organism:
Similar Structures:
Biological Unit for 6C2T: dimeric; determined by author and by software (PISA)
Molecular Components in 6C2T
Label Count Molecule
Proteins (2 molecules)
2
Aurora Kinase a
(Gene symbol: AURKA)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
(2S,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-2-methyl-4-({3-[(1,3-thiazol-2-yl)amino]isoquinolin-1-yl}methyl)piperidine-4-carboxylic acid(2S,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-2-methyl-4-({3-[(1,3-thiazol-2-yl)amino]isoquinolin-1-yl}methyl)piperidine-4-carboxylic acid
2
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303