5Z57: Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom

PDB ID: 5Z57Download
MMDB ID: 171438
PDB Deposition Date: 2018/1/17
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 6.5  Å
Source Organism:
unidentified adenovirus
Similar Structures:
Biological Unit for 5Z57: 57-meric; determined by author
Molecular Components in 5Z57
Label Count Molecule
Proteins (53 molecules)
1
Pre-mrna-processing-splicing Factor 8
Molecule annotation
1
116 KDA U5 Small Nuclear Ribonucleoprotein Component
Molecule annotation
1
U5 Small Nuclear Ribonucleoprotein 200 KDA Helicase
Molecule annotation
1
U5 Small Nuclear Ribonucleoprotein 40 KDA Protein
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D3
Molecule annotation
2
Small Nuclear Ribonucleoprotein-associated Proteins B and B'
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D1
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D2
Molecule annotation
2
Small Nuclear Ribonucleoprotein F
Molecule annotation
2
Small Nuclear Ribonucleoprotein E
Molecule annotation
2
Small Nuclear Ribonucleoprotein G
Molecule annotation
1
U2 Small Nuclear Ribonucleoprotein A'
Molecule annotation
1
U2 Small Nuclear Ribonucleoprotein B''
Molecule annotation
1
Splicing Factor 3A Subunit 3
Molecule annotation
1
Splicing Factor 3A Subunit 1
Molecule annotation
1
Splicing Factor 3A Subunit 2
Molecule annotation
1
Splicing Factor 3B Subunit 1
Molecule annotation
1
Splicing Factor 3B Subunit 2
Molecule annotation
1
Splicing Factor 3B Subunit 3
Molecule annotation
1
Splicing Factor 3B Subunit 4
Molecule annotation
1
Splicing Factor 3B Subunit 6
Molecule annotation
1
PHD Finger-like Domain-containing Protein 5A
Molecule annotation
1
Splicing Factor 3B Subunit 5
Molecule annotation
1
Crooked Neck-like Protein 1
Molecule annotation
1
Cell Division Cycle 5-like Protein
Molecule annotation
4
Pre-mrna-processing Factor 19
Molecule annotation
1
Pre-mrna-splicing Factor Spf27
Molecule annotation
1
Pre-mrna-splicing Factor Syf1
Molecule annotation
1
Intron-binding Protein Aquarius
Molecule annotation
1
Protein Bud31 Homolog
Molecule annotation
1
Pre-mrna-splicing Factor Rbm22
Molecule annotation
1
Spliceosome-associated Protein Cwc15 Homolog
Molecule annotation
1
Skip
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase-like 1
Molecule annotation
1
Pleiotropic Regulator 1
Molecule annotation
1
Serine/arginine Repetitive Matrix Protein 2
Molecule annotation
1
Pre-mrna-splicing Factor Cwc22 Homolog
Molecule annotation
1
Pre-mrna-processing Factor 17
Molecule annotation
1
Smad Nuclear-interacting Protein 1
Molecule annotation
1
RNA-binding Motif Protein, X-linked 2
Molecule annotation
1
Bud13 Homolog
Molecule annotation
1
Pre-mrna-splicing Factor Atp-dependent RNA Helicase Dhx16
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase E
Molecule annotation
Nucleotides(4 molecules)
1
U5 Snrna
Molecule annotation
1
U6 Snrna
Molecule annotation
1
Pre-mrna
Molecule annotation
1
U2 Snrna
Molecule annotation
Chemicals and Non-standard biopolymers (19 molecules)
1
1
1
6
10
* Click molecule labels to explore molecular sequence information.

Citing MMDB