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5WZZ:
The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation
PDB ID:
5WZZ
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MMDB ID:
153790
PDB Deposition Date:
2017/1/19
Updated in MMDB:
2023/11
Experimental Method:
x-ray diffraction
Resolution:
2.103 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 5WZZ: dimeric; determined by author and by software (PISA)
Molecular Components in 5WZZ
Label
Count
Molecule
Proteins (2 molecules)
A
1
E3 Ubiquitin-protein Ligase Siah1
(Gene symbol:
SIAH1
)
G
1
Axin-1
(Gene symbol:
AXIN1
)
Chemicals and Non-standard biopolymers (2 molecules)
1
2
ZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303