NCBI
National Center for
Biotechnology Information
Search
5WZX:
Structural basis for a pentacyclic oleanane-type triterpenoid as a ligand of FXR
PDB ID:
5WZX
Download
MMDB ID:
157925
PDB Deposition Date:
2017/1/19
Updated in MMDB:
2018/12
Experimental Method:
x-ray diffraction
Resolution:
2.95 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 5WZX: dimeric; determined by author and by software (PISA)
Molecular Components in 5WZX
Label
Count
Molecule
Proteins (2 molecules)
A
1
Bile Acid Receptor
(Gene symbol:
NR1H4
)
C
1
Src2-3 Peptide From Nuclear Receptor Coactivator 2
(Gene symbol:
NCOA2
)
Chemicals and Non-standard biopolymers (4 molecules)
1
1
(4aR,6aR,6aS,6bS,8aS,9R,12aR,14bR)-2,2,6a,6b,9,12a-hexamethyl-10-oxidanylidene-1,3,4,5,6,6a,7,8,8a,9,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
2
3
(R,R)-2,3-BUTANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303