5V37: Crystal structure of SMYD3 with SAM and EPZ028862

PDB ID: 5V37Download
MMDB ID: 159910
PDB Deposition Date: 2017/3/6
Updated in MMDB: 2019/05
Experimental Method:
x-ray diffraction
Resolution: 1.42  Å
Source Organism:
Similar Structures:
Biological Unit for 5V37: monomeric; determined by author and by software (PISA)
Molecular Components in 5V37
Label Count Molecule
Protein (1 molecule)
1
Histone-lysine N-methyltransferase Smyd3
(Gene symbol: SMYD3)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
3
ZINC IONZINC ION
2
1
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
3
1
N-{(3-endo)-8-[(trans-4-aminocyclohexyl)sulfonyl]-8-azabicyclo[3.2.1]octan-3-yl}-5-cyclopropyl-1,2-oxazole-3-carboxamideN-{(3-endo)-8-[(trans-4-aminocyclohexyl)sulfonyl]-8-azabicyclo[3.2.1]octan-3-yl}-5-cyclopropyl-1,2-oxazole-3-carboxamide
4
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
6
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303