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5UFP:
Crystal structure of PT2399 bound to HIF2a-B*:ARNT-B* complex
PDB ID:
5UFP
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MMDB ID:
146866
PDB Deposition Date:
2017/1/5
Updated in MMDB:
2017/12
Experimental Method:
x-ray diffraction
Resolution:
1.9 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 5UFP: dimeric; determined by author
Molecular Components in 5UFP
Label
Count
Molecule
Proteins (2 molecules)
A
1
Endothelial PAS Domain-containing Protein 1
(Gene symbol:
EPAS1
)
B
1
Aryl Hydrocarbon Receptor Nuclear Translocator
(Gene symbol:
ARNT
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-({(1S)-7-[(difluoromethyl)sulfonyl]-2,2-difluoro-1-hydroxy-2,3-dihydro-1H-inden-4-yl}oxy)-5-fluorobenzonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303