5N21: Crystal structure of the BCL6 BTB domain in complex with pyrazolo-pyrimidine ligand

PDB ID: 5N21Download
MMDB ID: 150840
PDB Deposition Date: 2017/2/6
Updated in MMDB: 2017/06
Experimental Method:
x-ray diffraction
Resolution: 1.58  Å
Source Organism:
Similar Structures:
Biological Unit for 5N21: monomeric; determined by author
Molecular Components in 5N21
Label Count Molecule
Protein (1 molecule)
1
B-cell Lymphoma 6 Protein
(Gene symbol: BCL6)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
CHLORIDE IONCHLORIDE ION
2
2
2-[(2~{S})-1-[3-cyano-7-[(2-oxidanylidene-3,4-dihydro-1~{H}-quinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]pyrrolidin-2-yl]ethanoic acid2-[(2~{S})-1-[3-cyano-7-[(2-oxidanylidene-3,4-dihydro-1~{H}-quinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]pyrrolidin-2-yl]ethanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303