5LMK: Structure of phopsho-CDK2-cyclin A in complex with an ATP-competitive inhibitor

PDB ID: 5LMKDownload
MMDB ID: 180589
PDB Deposition Date: 2016/8/1
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 5LMK: dimeric; determined by software (PISA)
Molecular Components in 5LMK
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 2
(Gene symbol: CDK2)
Molecule annotation
1
Cyclin-a2
(Gene symbol: CCNA2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
4-[4-[3-bromanyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-5-yl]phenyl]benzamide4-[4-[3-bromanyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-5-yl]phenyl]benzamide
2
1
MONOTHIOGLYCEROLMONOTHIOGLYCEROL
3
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303