5AQG: Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues

PDB ID: 5AQGDownload
MMDB ID: 154531
PDB Deposition Date: 2015/9/22
Updated in MMDB: 2017/09
Experimental Method:
x-ray diffraction
Resolution: 2.24  Å
Source Organism:
Similar Structures:
Biological Unit for 5AQG: dimeric; determined by author and by software (PISA)
Molecular Components in 5AQG
Label Count Molecule
Proteins (2 molecules)
1
Heat Shock Cognate 71 KDA Protein
(Gene symbol: HSPA8)
Molecule annotation
1
BAG Family Molecular Chaperone Regulator 1
(Gene symbol: BAG1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
(2R,3R,4S,5R)-2-(3-AMINO-5-METHYL-1,4,5,6,8-PENTAAZAACENAPHTHYLEN-1(5H)-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL(2R,3R,4S,5R)-2-(3-AMINO-5-METHYL-1,4,5,6,8-PENTAAZAACENAPHTHYLEN-1(5H)-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL
2
3
GLYCEROLGLYCEROL
3
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
4
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303