5AM8: Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with amyloid-beta 4-10

PDB ID: 5AM8Download
MMDB ID: 135410
PDB Deposition Date: 2015/3/10
Updated in MMDB: 2016/04
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5AM8: dimeric; determined by author and by software (PISA)
Molecular Components in 5AM8
Label Count Molecule
Proteins (2 molecules)
1
Angiotensin-converting Enzyme
(Gene symbol: ACE)
Molecule annotation
1
Beta-amyloid Protein 42
(Gene symbol: APP)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
2
beta-D-mannopyranosebeta-D-mannopyranose
2
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
3
1
alpha-L-fucopyranosealpha-L-fucopyranose
4
2
HEXAETHYLENE GLYCOLHEXAETHYLENE GLYCOL
5
9
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
6
2
ZINC IONZINC ION
7
2
CHLORIDE IONCHLORIDE ION
8
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303