4ZGA: Structural Basis For Inhibition Of Human Autotaxin By Four Novel Compounds

PDB ID: 4ZGADownload
MMDB ID: 133300
PDB Deposition Date: 2015/4/22
Updated in MMDB: 2015/11
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 4ZGA: monomeric; determined by author
Molecular Components in 4ZGA
Label Count Molecule
Protein (1 molecule)
1
Ectonucleotide Pyrophosphatase/phosphodiesterase Family Member 2
(Gene symbol: ENPP2)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
N-Acetyl-D-GlucosamineN-Acetyl-D-Glucosamine
2
1
Zinc IonZinc Ion
3
2
Calcium IonCalcium Ion
4
1
1,2-Ethanediol1,2-Ethanediol
5
2
Thiocyanate IonThiocyanate Ion
6
1
Arachidonic AcidArachidonic Acid
7
1
(11as)-6-(4-Fluorobenzyl)-5,6,11,11a-Tetrahydro-1h-Imidazo[1',5':1,6]pyrido[3,4-B]indole-1,3(2h)-Dione(11as)-6-(4-Fluorobenzyl)-5,6,11,11a-Tetrahydro-1h-Imidazo[1',5':1,6]pyrido[3,4-B]indole-1,3(2h)-Dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303