4UYN: SAR156497 an exquisitely selective inhibitor of Aurora kinases

PDB ID: 4UYNDownload
MMDB ID: 180955
PDB Deposition Date: 2014/9/2
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 4UYN: monomeric; determined by software (PISA)
Molecular Components in 4UYN
Label Count Molecule
Protein (1 molecule)
1
Aurora Kinase a
(Gene symbol: AURKA)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
ethyl (9S)-9-[5-(1H-benzimidazol-2-ylsulfanyl)furan-2-yl]-8-hydroxy-5,6,7,9-tetrahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylateethyl (9S)-9-[5-(1H-benzimidazol-2-ylsulfanyl)furan-2-yl]-8-hydroxy-5,6,7,9-tetrahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303