4UY1: Novel pyrazole series of group X Secretory Phospholipase A2 (sPLA2-X) inhibitors

PDB ID: 4UY1Download
MMDB ID: 123927
PDB Deposition Date: 2014/8/28
Updated in MMDB: 2014/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 4UY1: monomeric; determined by author and by software (PISA)
Molecular Components in 4UY1
Label Count Molecule
Protein (1 molecule)
1
Group 10 Secretory Phospholipase A2
(Gene symbol: PLA2G10)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
CALCIUM IONCALCIUM ION
2
2
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
3
4
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
1
5-(2,5-DIMETHYL-3-THIENYL)-1H-PYRAZOLE-3-CARBOXAMIDE5-(2,5-DIMETHYL-3-THIENYL)-1H-PYRAZOLE-3-CARBOXAMIDE
5
3
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303