4QT1: JAK3 kinase domain in complex with 1-[(3S)-1-isobutylsulfonyl-3-piperidyl]-3-(5H-pyrrolo[2,3-b]pyrazin-2-yl)urea

PDB ID: 4QT1Download
MMDB ID: 129559
PDB Deposition Date: 2014/7/7
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 4QT1: monomeric; determined by author and by software (PISA)
Molecular Components in 4QT1
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Jak3
(Gene symbol: JAK3)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-{(3S)-1-[(2-methylpropyl)sulfonyl]piperidin-3-yl}-3-(5H-pyrrolo[2,3-b]pyrazin-2-yl)urea1-{(3S)-1-[(2-methylpropyl)sulfonyl]piperidin-3-yl}-3-(5H-pyrrolo[2,3-b]pyrazin-2-yl)urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303