4QO7: Lactate Dehydrogenase A in complex with substituted 3-Hydroxy-2-mercaptocyclohex-2-enone compound 7

PDB ID: 4QO7Download
MMDB ID: 121593
PDB Deposition Date: 2014/6/19
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.14  Å
Source Organism:
Similar Structures:
Biological Unit for 4QO7: tetrameric; determined by author and by software (PISA)
Molecular Components in 4QO7
Label Count Molecule
Proteins (4 molecules)
4
L-lactate Dehydrogenase a Chain
(Gene symbol: LDHA)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
2
3
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
3
3
trans-2-[(2-nitrophenyl)sulfanyl]-5-phenylcyclohexane-1,3-dionetrans-2-[(2-nitrophenyl)sulfanyl]-5-phenylcyclohexane-1,3-dione
4
1
(2S)-2-HYDROXYPROPANOIC ACID(2S)-2-HYDROXYPROPANOIC ACID
5
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303