4OQB: Structure of Human PARP-1 bound to a DNA double strand break in complex with (2Z)-2-{4-[2-(morpholin-4-yl)ethoxy]benzylidene}-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide

PDB ID: 4OQBDownload
MMDB ID: 121175
PDB Deposition Date: 2014/2/7
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 3.362  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 4OQB: tetrameric; determined by author
Molecular Components in 4OQB
Label Count Molecule
Proteins (2 molecules)
1
Poly [adp-ribose] Polymerase 1
Molecule annotation
1
Poly [adp-ribose] Polymerase 1
Molecule annotation
Nucleotides(2 molecules)
2
DNA (26-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
ZINC IONZINC ION
2
1
(2Z)-2-{4-[2-(morpholin-4-yl)ethoxy]benzylidene}-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide(2Z)-2-{4-[2-(morpholin-4-yl)ethoxy]benzylidene}-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303