4OAV: Complete human RNase L in complex with 2-5A (5'-ppp heptamer), AMPPCP and RNA substrate

PDB ID: 4OAVDownload
MMDB ID: 118307
PDB Deposition Date: 2014/1/6
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 4OAV: tetrameric; determined by author and by software (PISA)
Molecular Components in 4OAV
Label Count Molecule
Proteins (2 molecules)
2
Protein (Rnase L)
Molecule annotation
Nucleotides(2 molecules)
2
RNA (5'-r(p*(po4)p*(po4)p*ap*ap*ap*ap*(po4))-2')
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
2
4
MAGNESIUM IONMAGNESIUM ION
3
1
(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-2-({[(S)-hydroxy{[(2R,3S,4S)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl]oxy}phosphoryl]oxy}methyl)tetrahydrofuran-3-yl dihydrogen phosphate(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-2-({[(S)-hydroxy{[(2R,3S,4S)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl]oxy}phosphoryl]oxy}methyl)tetrahydrofuran-3-yl dihydrogen phosphate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303