4NTX: Structure of acid-sensing ion channel in complex with snake toxin and amiloride

PDB ID: 4NTXDownload
MMDB ID: 117717
PDB Deposition Date: 2013/12/2
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.27  Å
Source Organism:
Micrurus tener tener▼
Similar Structures:
Biological Unit for 4NTX: trimeric; determined by author and by software (PISA)
Molecular Components in 4NTX
Label Count Molecule
Proteins (3 molecules)
1
Acid-sensing Ion Channel 1
Molecule annotation
1
Neurotoxin Mittx-alpha
Molecule annotation
1
Basic Phospholipase A2 Homolog Tx-beta
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
CHLORIDE IONCHLORIDE ION
3
3
SODIUM IONSODIUM ION
4
1
HEXAETHYLENE GLYCOLHEXAETHYLENE GLYCOL
5
3
3,5-DIAMINO-N-(AMINOIMINOMETHYL)-6-CHLOROPYRAZINECARBOXAMIDE3,5-DIAMINO-N-(AMINOIMINOMETHYL)-6-CHLOROPYRAZINECARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303