4NM7: Crystal structure of GSK-3/Axin complex bound to phosphorylated Wnt receptor LRP6 e-motif

PDB ID: 4NM7Download
MMDB ID: 118642
PDB Deposition Date: 2013/11/14
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 4NM7: trimeric; determined by author and by software (PISA)
Molecular Components in 4NM7
Label Count Molecule
Proteins (3 molecules)
1
Gsk3b Protein
(Gene symbol: GSK3B)
Molecule annotation
1
Axin-1
(Gene symbol: AXIN1)
Molecule annotation
1
Phosphorylated WNT Receptor Lrp6 E-motif
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
2
3
GLYCEROLGLYCEROL
3
2
MAGNESIUM IONMAGNESIUM ION
4
1
CHLORIDE IONCHLORIDE ION
5
1
2,3-DIHYDROXY-1,4-DITHIOBUTANE2,3-DIHYDROXY-1,4-DITHIOBUTANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303