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4NGD:
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 12-mer siRNA having 5'-p and UU-3' ends (1.95 Angstrom resolution)
PDB ID:
4NGD
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MMDB ID:
118059
PDB Deposition Date:
2013/11/1
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
1.958 Å
Source Organism:
synthetic construct
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Taxonomy
Molecule
synthetic construct
B
Homo sapiens
A
Similar Structures:
VAST+
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Biological Unit for 4NGD: trimeric; determined by author
Molecular Components in 4NGD
Label
Count
Molecule
Protein (1 molecule)
A
1
Endoribonuclease Dicer
Nucleotides(2 molecules)
B
B_0
2
5'-r(p*gp*cp*gp*ap*ap*up*up*cp*gp*cp*up*u)-3'
Chemicals and Non-standard biopolymers (5 molecules)
1
2
SULFATE ION
2
3
DI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303