4G1Q: Crystal structure of HIV-1 reverse transcriptase (RT) in complex with Rilpivirine (TMC278, Edurant), a non-nucleoside rt-inhibiting drug

PDB ID: 4G1QDownload
MMDB ID: 107317
PDB Deposition Date: 2012/7/11
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.51  Å
Source Organism:
Similar Structures:
Biological Unit for 4G1Q: dimeric; determined by author and by software (PISA)
Molecular Components in 4G1Q
Label Count Molecule
Proteins (2 molecules)
1
Reverse Transcriptase/ribonuclease H
Molecule annotation
1
P51 RT
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
1
4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile
2
6
SULFATE IONSULFATE ION
3
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303