4DKL: Crystal structure of the mu-opioid receptor bound to a morphinan antagonist

PDB ID: 4DKLDownload
MMDB ID: 98262
PDB Deposition Date: 2012/2/3
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 4DKL: dimeric; determined by author and by software (PISA)
Molecular Components in 4DKL
Label Count Molecule
Proteins (2 molecules)
2
Mu-type Opioid Receptor, Lysozyme Chimera
(Gene symbol: e)
Molecule annotation
Chemicals and Non-standard biopolymers (35 molecules)
1
2
methyl 4-{[(5beta,6alpha)-17-(cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6-yl]amino}-4-oxobutanoatemethyl 4-{[(5beta,6alpha)-17-(cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6-yl]amino}-4-oxobutanoate
2
24
SULFATE IONSULFATE ION
3
2
CHOLESTEROLCHOLESTEROL
4
4
[(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate[(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate
5
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
6
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303