4BXK: Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with a domain-specific inhibitor

PDB ID: 4BXKDownload
MMDB ID: 113517
PDB Deposition Date: 2013/7/12
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 4BXK: monomeric; determined by author and by software (PISA)
Molecular Components in 4BXK
Label Count Molecule
Protein (1 molecule)
1
Angiotensin-converting Enzyme
(Gene symbol: ACE)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
9
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
alpha-L-fucopyranosealpha-L-fucopyranose
3
1
beta-D-mannopyranosebeta-D-mannopyranose
4
4
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
1
HEXAETHYLENE GLYCOLHEXAETHYLENE GLYCOL
6
1
[3-[[(2S)-1-azanyl-1-oxidanylidene-propan-2-yl]amino]-2-methyl-3-oxidanylidene-propyl]-[(1R)-1-[[(2R)-2-azanyl-3-(1H-1,2,3,4-tetrazol-5-yl)propanoyl]amino]-2-phenyl-ethyl]phosphinic acid[3-[[(2S)-1-azanyl-1-oxidanylidene-propan-2-yl]amino]-2-methyl-3-oxidanylidene-propyl]-[(1R)-1-[[(2R)-2-azanyl-3-(1H-1,2,3,4-tetrazol-5-yl)propanoyl]amino]-2-phenyl-ethyl]phosphinic acid
7
1
ZINC IONZINC ION
8
1
CHLORIDE IONCHLORIDE ION
9
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303