4BDE: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2)

PDB ID: 4BDEDownload
MMDB ID: 111217
PDB Deposition Date: 2012/10/5
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.55  Å
Source Organism:
Similar Structures:
Biological Unit for 4BDE: monomeric; determined by author and by software (PISA)
Molecular Components in 4BDE
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Chk2
(Gene symbol: CHEK2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
NITRATE IONNITRATE ION
2
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
6-METHYLQUINAZOLIN-4-AMINE6-METHYLQUINAZOLIN-4-AMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303