4APH: Human angiotensin-converting enzyme in complex with angiotensin-II

PDB ID: 4APHDownload
MMDB ID: 104000
PDB Deposition Date: 2012/4/3
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.99  Å
Source Organism:
Similar Structures:
Biological Unit for 4APH: dimeric; determined by author and by software (PISA)
Molecular Components in 4APH
Label Count Molecule
Proteins (2 molecules)
1
Angiotensin-converting Enzyme
(Gene symbol: ACE)
Molecule annotation
1
Angiotensin-2
(Gene symbol: AGT)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
2
CHLORIDE IONCHLORIDE ION
4
1
ZINC IONZINC ION
5
1
2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL
6
5
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303