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4AFE:
Nek2 bound to hybrid compound 21
PDB ID:
4AFE
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MMDB ID:
99046
PDB Deposition Date:
2012/1/19
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2.597 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4AFE: monomeric; determined by author and by software (PISA)
Molecular Components in 4AFE
Label
Count
Molecule
Protein (1 molecule)
A
1
Serine/threonine-protein Kinase Nek2
(Gene symbol:
NEK2
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
4-(2-AMINO-5-{4-[(DIMETHYLAMINO)METHYL]THIOPHEN-2-YL}PYRIDIN-3-YL)-2-{[(1R,2Z)-4,4,4-TRIFLUORO-1-METHYLBUT-2-EN-1-YL]OXY}BENZAMIDE
2
1
1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303