3ZRA: Structural basis for agonism and antagonism for a set of chemically related progesterone receptor modulators

PDB ID: 3ZRADownload
MMDB ID: 92812
PDB Deposition Date: 2011/6/15
Updated in MMDB: 2011/10
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 3ZRA: monomeric; determined by author and by software (PISA)
Molecular Components in 3ZRA
Label Count Molecule
Protein (1 molecule)
1
Progesterone Receptor
(Gene symbol: PGR)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
N-{(1R)-1-[4-(2-CHLORO-5-FLUOROPYRIDIN-3-YL)PHENYL]ETHYL}-3,5-DIMETHYLISOXAZOLE-4-SULFONAMIDEN-{(1R)-1-[4-(2-CHLORO-5-FLUOROPYRIDIN-3-YL)PHENYL]ETHYL}-3,5-DIMETHYLISOXAZOLE-4-SULFONAMIDE
2
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303