3V4V: crystal structure of a4b7 headpiece complexed with Fab ACT-1 and RO0505376

PDB ID: 3V4VDownload
MMDB ID: 96406
PDB Deposition Date: 2011/12/15
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 3V4V: tetrameric; determined by author
Molecular Components in 3V4V
Label Count Molecule
Proteins (4 molecules)
1
Integrin Alpha-4
Molecule annotation
1
Integrin Beta-7
Molecule annotation
1
Monoclonal Antibody Act-1 Heavy Chain
Molecule annotation
1
Monoclonal Antibody Act-1 Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (22 molecules)
1
11
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
beta-D-mannopyranosebeta-D-mannopyranose
3
1
alpha-D-mannopyranosealpha-D-mannopyranose
4
5
CALCIUM IONCALCIUM ION
5
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
6
1
MAGNESIUM IONMAGNESIUM ION
7
1
N-(2,6-dichlorobenzoyl)-4-[1,6-dimethyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]-L-phenylalanineN-(2,6-dichlorobenzoyl)-4-[1,6-dimethyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]-L-phenylalanine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303