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3U2O:
Dihydroorotate Dehydrogenase (DHODH) crystal structure in complex with small molecule inhibitor
PDB ID:
3U2O
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MMDB ID:
95096
PDB Deposition Date:
2011/10/4
Updated in MMDB:
2011/12
Experimental Method:
x-ray diffraction
Resolution:
2.18 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3U2O: monomeric; determined by author and by software (PISA)
Molecular Components in 3U2O
Label
Count
Molecule
Protein (1 molecule)
A
1
Dihydroorotate Dehydrogenase (Quinone), Mitochondrial
(Gene symbol:
DHODH
)
Chemicals and Non-standard biopolymers (8 molecules)
1
1
FLAVIN MONONUCLEOTIDE
2
1
OROTIC ACID
3
1
methyl 4-{[(2Z)-2-cyano-3-hydroxypent-2-enoyl]amino}-4'-fluorobiphenyl-2-carboxylate
4
3
ACETATE ION
5
2
SULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303