3SP6: Structural basis for iloprost as a dual PPARalpha/delta agonist

PDB ID: 3SP6Download
MMDB ID: 92241
PDB Deposition Date: 2011/7/1
Updated in MMDB: 2011/07
Experimental Method:
x-ray diffraction
Resolution: 2.21  Å
Source Organism:
Similar Structures:
Biological Unit for 3SP6: dimeric; determined by author and by software (PISA)
Molecular Components in 3SP6
Label Count Molecule
Proteins (2 molecules)
1
Peroxisome Proliferator-activated Receptor Alpha
(Gene symbol: PPARA)
Molecule annotation
1
Peroxisome Proliferator-activated Receptor Gamma Coactivator 1-beta
(Gene symbol: PPARGC1B)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S,4R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]hexahydropentalen-2(1H)-ylidene]pentanoic acid(5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S,4R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]hexahydropentalen-2(1H)-ylidene]pentanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303