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3SIE:
Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors
PDB ID:
3SIE
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MMDB ID:
92955
PDB Deposition Date:
2011/6/17
Updated in MMDB:
2011/08
Experimental Method:
x-ray diffraction
Resolution:
1.93 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 3SIE: monomeric; determined by author and by software (PISA)
Molecular Components in 3SIE
Label
Count
Molecule
Protein (1 molecule)
A
1
Cgmp-specific 3',5'-cyclic Phosphodiesterase
(Gene symbol:
PDE5A
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-bromo-6-ethyl-2-{5-[(4-methylpiperazin-1-yl)sulfonyl]-2-propoxyphenyl}pyrimidin-4(3H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303