3S45: wild-type HIV-2 protease with antiviral drug amprenavir

PDB ID: 3S45Download
MMDB ID: 98131
PDB Deposition Date: 2011/5/18
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.51  Å
Source Organism:
Similar Structures:
Biological Unit for 3S45: dimeric; determined by author and by software (PISA)
Molecular Components in 3S45
Label Count Molecule
Proteins (2 molecules)
2
Protease
Molecule annotation
Chemicals and Non-standard biopolymers (23 molecules)
1
1
SODIUM IONSODIUM ION
2
8
CHLORIDE IONCHLORIDE ION
3
6
IMIDAZOLEIMIDAZOLE
4
7
ZINC IONZINC ION
5
1
{3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER{3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303