3OYJ: Crystal structure of the PFV S217Q mutant intasome in complex with magnesium and the INSTI MK2048

PDB ID: 3OYJDownload
MMDB ID: 86321
PDB Deposition Date: 2010/9/23
Updated in MMDB: 2010/12
Experimental Method:
x-ray diffraction
Resolution: 2.68  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3OYJ: octameric; determined by author and by software (PISA)
Molecular Components in 3OYJ
Label Count Molecule
Proteins (4 molecules)
4
PFV Integrase
Molecule annotation
Nucleotides(4 molecules)
2
DNA (5'-d(*ap*tp*tp*gp*tp*cp*ap*tp*gp*gp*ap*ap*tp*tp*tp*cp*gp*cp*a)-3')
Molecule annotation
2
DNA (5'-d(*tp*gp*cp*gp*ap*ap*ap*tp*tp*cp*cp*ap*tp*gp*ap*cp*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
2
ZINC IONZINC ION
2
4
SULFATE IONSULFATE ION
3
8
GLYCEROLGLYCEROL
4
2
AMMONIUM IONAMMONIUM ION
5
6
MAGNESIUM IONMAGNESIUM ION
6
2
(6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide(6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303