3MIY: X-ray crystal structure of ITK complexed with sunitinib

PDB ID: 3MIYDownload
MMDB ID: 83074
PDB Deposition Date: 2010/4/12
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 1.67  Å
Source Organism:
Similar Structures:
Biological Unit for 3MIY: monomeric; determined by author and by software (PISA)
Molecular Components in 3MIY
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Itk/tsk
(Gene symbol: ITK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamideN-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303