3LJ2: IRE1 complexed with JAK Inhibitor I

PDB ID: 3LJ2Download
MMDB ID: 82016
PDB Deposition Date: 2010/1/25
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 3.33  Å
Source Organism:
Similar Structures:
Biological Unit for 3LJ2: dimeric; determined by author and by software (PISA)
Molecular Components in 3LJ2
Label Count Molecule
Proteins (2 molecules)
2
Serine/threonine-protein Kinase/endoribonuclease Ire1
(Gene symbol: IRE1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE (Link to PubChem not yet available)2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303