3LE9: Crystal structure of the catalytic domain of TACE with Indazolinone-phenyl-hydantoin inhibitor

PDB ID: 3LE9Download
MMDB ID: 87146
PDB Deposition Date: 2010/1/14
Updated in MMDB: 2010/12
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 3LE9: monomeric; determined by author and by software (PISA)
Molecular Components in 3LE9
Label Count Molecule
Protein (1 molecule)
1
Disintegrin and Metalloproteinase Domain-containing Protein 17
(Gene symbol: ADAM17)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC IONZINC ION
2
1
(5R)-5-[(5-methoxy-3-oxo-1,3-dihydro-2H-indazol-2-yl)methyl]-5-phenylimidazolidine-2,4-dione(5R)-5-[(5-methoxy-3-oxo-1,3-dihydro-2H-indazol-2-yl)methyl]-5-phenylimidazolidine-2,4-dione
3
1
ISOPROPYL ALCOHOLISOPROPYL ALCOHOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303