3G6E: Co-crystal structure of Homoharringtonine bound to the large ribosomal subunit

PDB ID: 3G6EDownload
MMDB ID: 71420
PDB Deposition Date: 2009/2/6
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 3G6E: 31-meric; determined by author
Molecular Components in 3G6E
Label Count Molecule
Proteins (29 molecules)
1
50S Ribosomal Protein L2P
(Gene symbol: RR_RS11185)
Molecule annotation
1
50S Ribosomal Protein L3P
(Gene symbol: rpl3p)
Molecule annotation
1
50S Ribosomal Protein L4P
(Gene symbol: rpl4p)
Molecule annotation
1
50S Ribosomal Protein L5P
(Gene symbol: RR_RS11135)
Molecule annotation
1
50S Ribosomal Protein L6P
(Gene symbol: RR_RS11120)
Molecule annotation
1
50S Ribosomal Protein L7ae
(Gene symbol: RR_RS04485)
Molecule annotation
1
50S Ribosomal Protein L10e
(Gene symbol: RR_RS10280)
Molecule annotation
1
50S Ribosomal Protein L10e
(Gene symbol: RR_RS14520)
Molecule annotation
1
50S Ribosomal Protein L11p
(Gene symbol: RR_RS10270)
Molecule annotation
1
50S Ribosomal Protein L13p
(Gene symbol: RR_RS04320)
Molecule annotation
1
50S Ribosomal Protein L14p
(Gene symbol: RR_RS11150)
Molecule annotation
1
50S Ribosomal Protein L15p
(Gene symbol: RR_RS11090)
Molecule annotation
1
50S Ribosomal Protein L15e
(Gene symbol: RR_RS13190)
Molecule annotation
1
50S Ribosomal Protein L18p
(Gene symbol: RR_RS11105)
Molecule annotation
1
50S Ribosomal Protein L18e
(Gene symbol: RR_RS04315)
Molecule annotation
1
50S Ribosomal Protein L19e
(Gene symbol: RR_RS11110)
Molecule annotation
1
50S Ribosomal Protein L21e
(Gene symbol: RR_RS05195)
Molecule annotation
1
50S Ribosomal Protein L22p
(Gene symbol: RR_RS11175)
Molecule annotation
1
50S Ribosomal Protein L23p
(Gene symbol: RR_RS11190)
Molecule annotation
1
50S Ribosomal Protein L24p
(Gene symbol: RR_RS11145)
Molecule annotation
1
50S Ribosomal Protein L24e
(Gene symbol: RR_RS04495)
Molecule annotation
1
50S Ribosomal Protein L29p
(Gene symbol: rpmC)
Molecule annotation
1
50S Ribosomal Protein L30p
(Gene symbol: rpmD)
Molecule annotation
1
50S Ribosomal Protein L31e
(Gene symbol: RR_RS17815)
Molecule annotation
1
50S Ribosomal Protein L32e
(Gene symbol: RR_RS11115)
Molecule annotation
1
50S Ribosomal Protein L37ae
(Gene symbol: RR_RS11475)
Molecule annotation
1
50S Ribosomal Protein L37e
Molecule annotation
1
50S Ribosomal Protein L39e
(Gene symbol: RR_RS17810)
Molecule annotation
1
50S Ribosomal Protein L44e
(Gene symbol: RR_RS19595)
Molecule annotation
Nucleotides(2 molecules)
1
23S Ribosomal RNA
Molecule annotation
1
5S Ribosomal RNA
Molecule annotation
Chemicals and Non-standard biopolymers (306 molecules)
1
93
MAGNESIUM IONMAGNESIUM ION
2
2
POTASSIUM IONPOTASSIUM ION
3
75
SODIUM IONSODIUM ION
4
22
CHLORIDE IONCHLORIDE ION
5
108
STRONTIUM IONSTRONTIUM ION
6
1
(3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine(3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine
7
5
CADMIUM IONCADMIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303