3EJ1: CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor

PDB ID: 3EJ1Download
MMDB ID: 67508
PDB Deposition Date: 2008/9/17
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 3.22  Å
Source Organism:
Similar Structures:
Biological Unit for 3EJ1: dimeric; determined by author and by software (PISA)
Molecular Components in 3EJ1
Label Count Molecule
Proteins (2 molecules)
1
Cell Division Protein Kinase 2
(Gene symbol: CDK2)
Molecule annotation
1
Cyclin-a2
(Gene symbol: CCNA2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amineN-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303