3E7C: Glucocorticoid Receptor LBD bound to GSK866

PDB ID: 3E7CDownload
MMDB ID: 68143
PDB Deposition Date: 2008/8/18
Updated in MMDB: 2008/12
Experimental Method:
x-ray diffraction
Resolution: 2.15  Å
Source Organism:
Similar Structures:
Biological Unit for 3E7C: tetrameric; determined by author and by software (PISA)
Molecular Components in 3E7C
Label Count Molecule
Proteins (4 molecules)
2
Glucocorticoid Receptor
(Gene symbol: NR3C1)
Molecule annotation
2
Nuclear Receptor Coactivator 2
(Gene symbol: NCOA2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
5-amino-N-[(2S)-2-({[(2,6-dichlorophenyl)carbonyl](ethyl)amino}methyl)-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide5-amino-N-[(2S)-2-({[(2,6-dichlorophenyl)carbonyl](ethyl)amino}methyl)-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide
2
3
GLYCEROLGLYCEROL
3
1
Molecule information is not available.
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303