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3E34:
Protein farnesyltransferase complexed with FPP and ethylenediamine-scaffold inhibitor 10
PDB ID:
3E34
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MMDB ID:
70118
PDB Deposition Date:
2008/8/6
Updated in MMDB:
2011/05
Experimental Method:
x-ray diffraction
Resolution:
2.05 Å
Source Organism:
Rattus norvegicus
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3E34: monomeric; determined by author
Molecular Components in 3E34
Label
Count
Molecule
Protein (1 molecule)
A
1
Protein Farnesyltransferase/geranylgeranyltransferase Type-1 Subunit Alpha
(Gene symbol:
Fnta
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
FARNESYL DIPHOSPHATE
2
1
3-{2'-[{[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl}(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)sulfamoyl]biphenyl-3-yl}propanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303