3D94: Crystal structure of the insulin-like growth factor-1 receptor kinase in complex with PQIP

PDB ID: 3D94Download
MMDB ID: 65752
PDB Deposition Date: 2008/5/26
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 3D94: dimeric; determined by author and by software (PISA)
Molecular Components in 3D94
Label Count Molecule
Proteins (2 molecules)
2
Insulin-like Growth Factor 1 Receptor Beta Chain
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
CALCIUM IONCALCIUM ION
2
2
3-[cis-3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine3-[cis-3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303