3CQW: Crystal Structure of Akt-1 complexed with substrate peptide and inhibitor

PDB ID: 3CQWDownload
MMDB ID: 64702
PDB Deposition Date: 2008/4/3
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 3CQW: dimeric; determined by author and by software (PISA)
Molecular Components in 3CQW
Label Count Molecule
Proteins (2 molecules)
1
Rac-alpha Serine/threonine-protein Kinase
(Gene symbol: AKT1)
Molecule annotation
1
Glycogen Synthase Kinase-3 Beta
(Gene symbol: GSK3B)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
MANGANESE (II) IONMANGANESE (II) ION
2
1
5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303