3APC: Crystal structure of human PI3K-gamma in complex with CH5132799

PDB ID: 3APCDownload
MMDB ID: 89814
PDB Deposition Date: 2010/10/14
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.544  Å
Source Organism:
Similar Structures:
Biological Unit for 3APC: monomeric; determined by author and by software (PISA)
Molecular Components in 3APC
Label Count Molecule
Protein (1 molecule)
1
Phosphatidylinositol-4,5-bisphosphate 3-kinase Catalytic Subunit Gamma Isoform
(Gene symbol: PIK3CG)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
5-(7-Methanesulfonyl-2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-ylamine5-(7-Methanesulfonyl-2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-ylamine
2
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303