3AH8: Structure of heterotrimeric G protein Galpha-q beta gamma in complex with an inhibitor YM-254890

PDB ID: 3AH8Download
MMDB ID: 83452
PDB Deposition Date: 2010/4/20
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3AH8: tetrameric; determined by author and by software (PISA)
Molecular Components in 3AH8
Label Count Molecule
Proteins (3 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1/guanine Nucleotide-binding Protein G(q) Subunit Alpha Chimeric Protein
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
Y
1
YM-254890
1
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303