2XVD: ephB4 kinase domain inhibitor complex

PDB ID: 2XVDDownload
MMDB ID: 91141
PDB Deposition Date: 2010/10/25
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 2XVD: monomeric; determined by author and by software (PISA)
Molecular Components in 2XVD
Label Count Molecule
Protein (1 molecule)
1
Ephrin Type-b Receptor 4
(Gene symbol: EPHB4)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
{4-METHYL-3-[(1-METHYLETHYL)(2-{[3-(METHYLSULFONYL)-5-MORPHOLIN-4-YLPHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENYL}METHANOL{4-METHYL-3-[(1-METHYLETHYL)(2-{[3-(METHYLSULFONYL)-5-MORPHOLIN-4-YLPHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENYL}METHANOL
2
3
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303