2VX1: ephB4 kinase domain inhibitor complex

PDB ID: 2VX1Download
MMDB ID: 67585
PDB Deposition Date: 2008/6/30
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.65  Å
Source Organism:
Similar Structures:
Biological Unit for 2VX1: monomeric; determined by author and by software (PISA)
Molecular Components in 2VX1
Label Count Molecule
Protein (1 molecule)
1
Ephrin Type-b Receptor 4
(Gene symbol: EPHB4)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
3-({4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL}AMINO)BENZAMIDE3-({4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL}AMINO)BENZAMIDE
2
3
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303